%0 Journal Article
%T Efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 Ctenocephalides felis flea strain infesting cats
%A Michael W Dryden
%A Patricia A Payne
%A Vicki Smith
%A Joe Hostetler
%J Parasites & Vectors
%D 2011
%I BioMed Central
%R 10.1186/1756-3305-4-174
%X In study #1 imidacloprid + moxidectin and the selamectin formulation provided 99.8% and 99.0% efficacy at 24 hours post-treatment. On day 28, the 24 hour efficacy of the selamectin formulation dropped to 87.1%, whereas the imidacloprid + moxidectin formulation provided 98.9% efficacy. At the 48 hour assessments following the 28 day infestations, efficacy of the imidacloprid + moxidectin and selamectin formulations was 96.8% and 98.3% respectively. In study # 2 the efficacy of the imidacloprid + moxidectin and selamectin formulations 12 hours after treatment was 100% and 69.4%, respectively. On day 28, efficacy of the imidacloprid + moxidectin and selamectin formulations 12 hours after infestation was 90.2% and 57.3%, respectively. In study #2 both formulations provided high levels of efficacy at the 24 hour post-infestation assessments, with selamectin and imidacloprid + moxidectin providing 95.3% and 97.5% efficacy, following infestations on day 28.At the 24 and 48 hour residual efficacy assessments, the imidacloprid + moxidectin and selamectin formulations were similarly highly efficacious. However, the imidacloprid + moxidectin formulation provided a significantly higher rate of flea kill against the KS1 flea strain infesting cats at every 12 hour post-infestation residual efficacy assessment. Both formulations should provide excellent flea control for an entire month on cats.Numerous animals that travel through neighborhoods, parks and yards carry Ctenocephalides felis (cat fleas), including feral cats and wildlife, such as opossums, raccoons, foxes, and coyotes [1]. These flea-infested animals are continuously depositing flea eggs in the outdoor environment. Within a few weeks, eggs deposited in protected areas may develop into adult fleas. If pets come in contact with these areas, they can rapidly acquire fleas. Once on a pet, the fleas will feed and mate, after which female fleas will begin laying eggs within as little as 24 hours [2]. After a few days, each
%U http://www.parasitesandvectors.com/content/4/1/174