%0 Journal Article
%T Efficacy of slow-release collar formulations of imidacloprid/flumethrin and deltamethrin and of spot-on formulations of fipronil/(s) - methoprene, dinotefuran/pyriproxyfen/permethrin and (s) ¨Cmethoprene/amitraz/fipronil against Rhipicephalus sanguineus and Ctenocephalides felis felis on dogs
%A Ivan G Horak
%A Josephus J Fourie
%A Dorothee Stanneck
%J Parasites & Vectors
%D 2012
%I BioMed Central
%R 10.1186/1756-3305-5-79
%X The first study comprised 4 groups of treated dogs and one untreated control group, and the second 3 groups of treated dogs and one control group. Each group consisted of 8 dogs. All dogs were infested with ticks and fleas at regular intervals. Ticks were counted 6£¿h, 18£¿h or 48£¿h after infestations and fleas 24£¿h after infestations. Efficacies of the treatments were calculated by comparison with the untreated control groups using standard descriptive statistics.The protective 48£¿h tick efficacy was 97.8% to 100% for the IVP (226£¿days), 69.3% to 97.4% for CP1 (170£¿days), 99.6% to 43.4% for CP2 (35£¿days) and 98% to 61.4% for CP3 (35£¿days).The protective 18£¿h tick efficacy was 98% to 99.6% for the IVP (71£¿days), 100% to 86.5% for CP4 (29£¿days), 100% to 72.8% for CP4 after re-treatment (35£¿days) and 98.8% to 54.3% for CP5 (35£¿days).The protective 6£¿h tick efficacy was 85.6% at Day 7 and 90.1% to 97.1% from Day 14 onwards for the IVP (70£¿days), 92.3% to 70.7% for CP4 (35£¿days), 97.5% to 65.2% for CP4 after re-treatment (35£¿days) and 95.1% to 51.8% for CP5 (35£¿days).The protective 24£¿h flea efficacy was 99.5/90.9% to 100% for the IVP (71/226£¿days), 66.7% to 83% for CP1 (170£¿days), 100% to 88.5% for CP2 (35£¿days), 100% to 73.3% for CP3 (35£¿days), 100% to 98.7% for CP4 (35£¿days), 100% to 87.5% for CP4 after re-treatment (35£¿days) and 100% to 79.5% for CP5 (35£¿days).These data suggest that the long-term efficacy provided by a medicated collar that is effective, is a means to overcome the fluctuating efficacy of spot-on treatments resulting from a lack of pet owner re-treatment compliance, and consequently protect animals successfully against ectoparasites and probably vector-borne diseases.
%K Fleas
%K Ticks
%K Efficacy
%K Imidacloprid
%K Flumethrin
%K Collar
%K Deltamethrin
%K Fipronil
%K Methoprene
%K Amitraz
%K Dinotefuran
%K Spot-on
%U http://www.parasitesandvectors.com/content/5/1/79/abstract