%0 Journal Article
%T Evaluation of the Biological Effects for Adding Cinnamon Volatile Oil and TBHQ as Antioxidant on RatsĄŻ Lipid Profiles
%A Mona M. Elshafie
%A Isis Azer Nawar
%A Muhammad A. Algamal
%A Samir Mohammad Ahmad
%J Asian Journal of Plant Sciences
%D 2012
%I 
%X Cardiovascular disease is one of the main health problems. Long term consumption of fried products increase the incidence of heart disease, synthetic antioxidants (TBHQ) were used to reduce oil oxidation but they have dangerous side effects. The current trend is to use plant volatile oils as a natural alternative that were found to have favourable taste and antioxidants. The effects of cinnamon volatile oil as a natural antioxidants were studied and also the major components of the volatile oil were identified using GC-MS. During the 45 days experimental period, rats were divided into 4 groups, fed a diet containing 15% oil that was either fresh oil (G1) or heated oil (G2) or heated oil mixed with 0.2% (TBHQ) (G3) and also cinnamon oil (G4). The parameters examined for studying the health effects of the cinnamon oil were, lipid profiles include assessing of total lipids, total cholesterol (TC), Triglycerides , HDL, LDL, VLDL and Atherogenic index. Also serum parameters uric acid, creatinine, bilirubin and glucose were measured. The results showed that the total lipid for (G2) was 117.47%, 113.6% for G3 and 105.1% for (G4) compared to (G1). Same pattern of effect for Triglyceride, (TC) reduced for (G4) to 91.14% comparing to (G1), HDL were insignificantly decreased in (G2, G3, G4) (20.63, 21.22, 23.03 mg dL-1) comparing to (G1) (26 mg dL-1). Adding cinnamon oil (G4) reduced LDL to 86.55% comparing to (G1). Also Atherogenic index was significantly decreased from 3.34 to 1.92 for G2 and G4 respectively. The effects of cinnamon oil on serum parameters found to be positive due to the detected improvements in (G4) compared to (G2). The GC-MS analysis of the cinnamon oil indicated that cinnamaldehyde is main compound in concentration of 64.21%. Adding cinnamon oil can improve lipid profiles which release the incidence of atherosclerosis.
%K lipid profiles
%K synthetic antioxidant
%K TBHQ
%K Cinnamon volatile oil
%K atherogenic index
%K atherosclerosis
%U http://docsdrive.com/pdfs/ansinet/ajps/2012/100-108.pdf