%0 Journal Article
%T Vitamin D in the light of current knowledge
%A Ayse Tellioglu
%A Sibel Basaran
%J Arsiv Kaynak Tarama Dergisi
%D 2013
%I Cukurova University
%X Vitamin D is an essential factor not only for homeostasis of calcium and phosphorus, but also regulates hundreds of genes involved in cell differentiation and cell proliferation through nuclear vitamin D receptor of its active form, 1,25-dihydroksyvitamin D3. Besides its beneficial effects on bone health, vitamin D contributes to the prevention of various malignancies, autoimmune and allergic diseases, cardiovascular and infectious diseases as a result of their anti-inflammatory and immune modulatory properties and effects on cytokine levels. Low vitamin D levels are associated with so many diseases such as malignancies, autoimmune disease, diabetes, hypertension and infectious disease. Current knowledge about vitamin D and the effects of vitamin D on musculoskeletal system and the other systems are discussed in this review. [Archives Medical Review Journal 2013; 22(2.000): 259-271]
%K 1
%K 25(OH)2D
%K Vitamin D
%K Vitamin D receptor
%U http://www.scopemed.org/fulltextpdf.php?mno=26967