%0 Journal Article
%T Bevacizumab (Avastin ) intracamerular en el manejo quir迆rgico del glaucoma neovascular Intracameral bevacizumab (Avastin ) in the management of neovascular glaucoma surgery
%A H. Fern芍ndez Jim谷nez-Ortiz
%A S. Perucho Martinez
%A N. Toledano Fern芍ndez
%A E. Martin Giral
%J Archivos de la Sociedad Espaˋola de Oftalmolog赤a
%D 2012
%I Scientific Electronic Library Online
%X Prop車sito: Describir una serie de casos con glaucoma neovascular que fueron tratados con bevacizumab intracamerular previo a la cirug赤a filtrante. Dise o: Descriptivo, retrospectivo, tipo serie de casos. M谷todos: Cinco ojos de cinco pacientes con glaucoma neovascular de cualquier causa candidatos a cirug赤a filtrante recibieron previamente una inyecci車n de bevacizumab (1,25mg/0,05ml) intracamerular como tratamiento de la neovascularizaci車n angular. Se describen los resultados observados a la semana y a las 4 semanas poscirug赤a. Resultados: Bevacizumab produjo una regresi車n importante de los neovasos y de la presi車n intraocular. Se detect車 un 迆nico caso de sangrado postoperatorio. Conclusiones: Bevacizumab intracamerular previo a cirug赤a filtrante de glaucoma disminuy車 la neovascularizaci車n del segmento anterior y la presi車n intraocular a las 4 semanas de su administraci車n y result車 eficaz en impedir el sangrado intra- y postoperatorio. Tambi谷n constituye una prometedora v赤a de investigaci車n para prevenir las complicaciones quir迆rgicas. Purpose: To describe a case series of neovascular glaucoma treated with intracameral bevacizumab prior to filtering surgery. Design: Descriptive, retrospective case series. Methods: Five eyes of 5 patients with neovascular glaucoma due to any cause candidates to filtering surgery who had previously received an injection of intracameral bevacizumab (1.25mg/0.05ml) as treatment for neovascularization of anterior chamber. Results observed one week and 4 weeks postsurgery are reported. Results: Bevacizumab produced regression of the angle neovascularization and the intraocular pressure. Only one case of postoperative bleeding was detected. Conclusions: Intracameral bevacizumab prior to filtering surgery of neovascular glaucoma diminished the neovascularization and intraocular pressure after 4 weeks of its administration and was effective in preventing intraoperative and postoperative bleeding. It also constitutes a promising way of investigation to prevent surgical complications.
%K Bevacizumab
%K Glaucoma neovascular
%K Cirug赤a filtrante
%K Antiangiog谷nicos
%K Inyecci車n intraocular
%K Bevacizumab
%K Glaucoma neovascular
%K Filtering surgery
%K Angiogenesis inhibitors
%K Injections intraocular
%U http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0365-66912012001200003