%0 Journal Article
%T Case report GravesĄŻ thyrotoxicosis in a patient with metastatic differentiated thyroid carcinoma and chronic lymphocytic leukaemia (CLL)
%A Jacek Makarewicz
%A SŁżawomir Mikosi¨˝ski
%A Antoni Rutkowski
%A Zbigniew Adamczewski
%J Archives of Medical Science
%D 2007
%I Termedia Publishing House
%X Thyrotoxicosis is rare in patients with thyroid carcinoma. A case is reported of a 66-year-old woman with GravesĄŻ disease, papillary thyroid carcinoma (PTC) with pulmonary metastases and chronic lymphocytic leukaemia (CLL). After thyroidectomy and antithyroid drug (ATD) withdrawal, thyrotoxicosis recurred. Treatment with ATD and 131I (six doses, 36.3 GBq in total) resulted in permanent hypothyroidism and significant destruction of lung metastases. The course of CLL was mild, but transient anaemia and thrombocytopenia were observed after 131I therapy. Pathomechanisms of thyrotoxicosis in patients with metastatic thyroid carcinoma, its treatment and its relation to CLL are presented.
%K thyroid carcinoma
%K thyrotoxicosis
%K metastases
%K radioiodine therapy
%K chronic lymphocytic leukaemia
%U http://www.termedia.pl/magazine.php?magazine_id=19&article_id=8492&magazine_subpage=FULL_TEXT