%0 Journal Article %T Impact of laughter on air trapping in severe chronic obstructive lung disease %A Martin H Brutsche %A Paul Grossman %A Rebekka E Mü %A ller %A Jan Wiegand %J International Journal of COPD %D 2008 %I Dove Medical Press %X Martin H Brutsche1, Paul Grossman2, Rebekka E M¨¹ller1, Jan Wiegand1, Pello3, Florent Baty1, Willibald Ruch41Pneumology; 2Psycho-Somatic Medicine, University Hospital Basel, Petersgraben, Basel, Switzerland; 3Pello, Clown, Basel, Switzerland; 4Psychology, University of Zurich, Department of Psychology, Zurich, SwitzerlandAbstract: Static and dynamic hyperinflation is an important factor of exertional dyspnea in patients with severe COPD. This proof-of-concept intervention trial sought to study whether laughter can reduce hyperinflation through repetitive expiratory efforts in patients with severe COPD. For small groups of patients with severe COPD (n = 19) and healthy controls (n = 10) Pello the clown performed a humor intervention triggering regular laughter. Plethysmography was done before and up to 24 hours after intervention. Laughing and smiling were quantified with video-analysis. Real-time breathing pattern was assessed with the LifeShirt , and the psychological impact of the intervention was monitored with self-administered questionnaires. The intervention led to a reduction of TLC in COPD (p = 0.04), but not in controls (p = 0.9). TLC reduction was due to a decline of the residual volume. Four (22 [CI 95% 7 to 46] %) patients were ¡Ư10% responders. The frequency of smiling and TLC at baseline were independent predictors of TLC response. The humor intervention improved cheerfulness, but not seriousness nor bad mood. In conclusion, smiling induced by a humor intervention was able to reduce hyperinflation in patients with severe COPD. A smiling-derived breathing technique might complement pursed-lips breathing in patients with symptomatic obstruction.Keywords: bronchodilator, cheerfulness, COPD, dyspnoea, humor, hyperinflation %U http://www.dovepress.com/impact-of-laughter-on-air-trapping-in-severe-chronic-obstructive-lung--a562