%0 Journal Article
%T Paepalanthus spp: antimycobacterial activity of extracts, methoxylated flavonoids and naphthopyranone fractions
%A Raquel R. D. Moreira
%A Gilmarcio Z. Martins
%A Rosemeire C. L. R. Pietro
%A Daisy N. Sato
%J Revista Brasileira de Farmacognosia
%D 2013
%I Sociedade Brasileira de Farmacognosia
%X Paepalanthus spp., Eriocaulaceae, are native plants from Brazil known as "sempre-vivas" (everlasting flowers). In this work, we evaluated the potential anti-mycobacterial activity of two methoxylated flavonoids (flavonoid 7-methylquercetagetin and 7-methylquercetagetin-4'-O-¦Â-D-glucopyranoside) isolated and identified from P. latipes and the naphthopyranone fractions from P. bromeliodes ethanolic extracts. The MIC value of 500 ¦Ìg/mL was verified for all compounds tested against M. tuberculosis H37Rv. For M. avium, the MIC value ranged from 1000-2000 ¦Ìg/mL excepting to naphthopyranone fractions with MIC of 500 ¦Ìg/mL. This is the first report of activity determination of Paepalanthus spp. flavonoids activity against Mycobacterium tuberculosis and M. avium.
%K flavonoids
%K Mycobacterium
%K naphthopyranone
%K Paepalanthus spp
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200010