%0 Journal Article %T The effect of physical activity on serum lipids, lipoprotein, and apolipoproteins %A Jerry Shearman %A Dominic Micklewright %A Jane Hardcastle %A Michael Hamlin %J Archives of Exercise in Health and Disease %D 2010 %I Research Centre in Physical Activity, Health and Leisure (CIAFEL) %X Objective: The aim of this study was to measure apolipoprotein-A1 and apolipoprotein-B serum concentrations during a physical activity program. Serum apolipoprotein concentrations may be a more sensitive indicator of coronary heart disease (CHD) risk than total cholesterol, triglycerides, low density lipoproteins and high density lipoproteins. Design: Thirty-seven sedentary, healthy adult males were randomly allocated to an exercise group (n=20) who underwent 12 weeks of aerobic physical activity or a sedentary group (n=17) who acted as non- exercising controls. Results: The exercise group increased their aerobic capacity (from 33¡À4 mL kg-1 min-1 to 40¡À4 mL kg-1 min-1) but the sedentary group did not. The percentage of body fat decreased in the exercise group (from 21.8% to 19.5%) but remained unchanged in the sedentary group. Serum cholesterol, lipoprotein and apolipoprotein concentrations did not change but serum triglyceride concentrations were reduced in the exercise group (from 1.8¡À1.3 mmol L-1 to 1.2¡À0.4 mmol L-1, p<0.05). The Apo-A1:Apo-B ratio increased in the exercise group (from 1.17¡À0.22 to 1.4¡À0.27, p<0.05) but not in the sedentary group. Conclusion: Apolipoprotein concentrations in sedentary males are no more sensitive than other serum lipid concentrations but are appropriate for monitoring CHD risk-factor change during short-term light exercise interventions. %K physical activity %K serum lipids %K apolipoproteins %U http://ciafel.fade.up.pt/ojs/index.php/AEHD/article/view/14/111