%0 Journal Article
%T Rice protein improves adiposity, body weight and reduces lipids level in rats through modification of triglyceride metabolism
%A Lin Yang
%A Jia-Hou Chen
%A Jie Lv
%A Qiong Wu
%A Tong Xu
%A Hua Zhang
%A Qiao-Hong Liu
%A Hong-Kun Yang
%J Lipids in Health and Disease
%D 2012
%I BioMed Central
%R 10.1186/1476-511x-11-24
%X Compared with CAS, plasma concentrations of glucose and lipids were significantly reduced by RP-feeding (P < 0.05), as well as hepatic accumulation of lipids (P < 0.05). RP-A and RP-E significantly depressed the hepatic activities of fatty acid synthase (FAS), glucose 6-phosphate dehydrogenase (G6PD) and malate dehydrogenase (MDH) (P < 0.05), whereas the activities of lipoprotein lipase (PL) and hepatic lipase (HL) were significantly stimulated (P < 0.05), as compared to CAS. Neither lipids level nor activities of enzymes were different between RP-A and RP-E (P > 0.05). There was a significant positive correlation between protein digestibility and deposit fat (r = 0.8567, P < 0.05), as well as the plasma TG concentration (r = 0.8627, P < 0.05).The present study demonstrates that rice protein can modify triglyceride metabolism, leading to an improvement of body weight and adiposity. Results suggest that the triglyceride-lowering action as well as the potential of anti-adiposity induced by rice protein is attributed to upregulation of lipolysis and downregulation of lipogenesis, and the lower digestibility of rice protein may be the main modulator responsible for the lipid-lowering action.Obesity is an indicator for the disorder of lipid metabolism and has become a worldwide epidemic [1,2]. To prevent the occurrence of the life style-related diseases, increasing evidences suggest that dietary components can improve lipid metabolism to control body weight and reduce deposit fat [3-5]. Compared with animal protein such as casein, soy protein has exhibited a beneficial effect on lipid metabolism to improve body weight and adiposity through suppressing hepatic lipogenic enzyme activity [6-8]. However, up to now, there is not yet a comprehensive understanding for a link of anti-adiposity and the consumption of rice protein, which is another major plant protein in the world.Rice is a staple cereal and widely consumed in the world. There is growing emphasis on the improvemen
%K Rice protein
%K Triglyceride
%K Lipogenesis
%K Lipolysis
%K Digestibility
%K Rats
%U http://www.lipidworld.com/content/11/1/24