%0 Journal Article %T Music and medicine: The effects of music on the human being %A Hans-Joachim Trappe %J Applied Cardiopulmonary Pathophysiology %D 2012 %I Pabst Science Publishers %X Music may not only improve quality of life but also effect changes in heart rate (HR) and heart rate variability (HRV). A greater modulation of HR and HRV was shown during musical performance compared to listening to music. Cerebral flow was significantly lower when listening to ¡°Va pensiero¡± from Verdi¡¯s ¡°Nabucco¡± (70.4¡À3.3 cm/s) compared to ¡°Libiam nei lieti calici¡± from Verdi¡¯s ¡°La Traviata¡± (70.2¡À3.1 cm/s) (p<0,02) or Bach¡¯s Cantata No. 169 Gott soll allein mein Herze haben¡° (70.9¡À2.9 cm/s) (p<0,02). There was no significant influence on cerebral flow in Beethoven¡¯s Ninth Symphony during rest (67.6¡À3.3 cm/s) or music (69.4¡À3.1 cm/s). Music significantly decreases the level of anxiety for patients in a preoperative setting compared to midazolam (STAI-X-1 score 36) (p<0.001). Listening to music while resting in bed after open-heart surgery leads to significant differences in cortisol levels between the music (484.4 mmol/l) and the non-music group (618.8 mmol/l) (p<0.02). %K music performance %K music perception %K quality of life %K music therapy %K cardiovascular system %U http://www.applied-cardiopulmonary-pathophysiology.com/fileadmin/downloads/acp-2012-2_20120517/03_trappe.pdf