%0 Journal Article
%T Silver 109 Ag Nanoparticles for Matrix-Less Mass Spectrometry of Nucleosides and Nucleic Bases
%A Joanna Nizio£¿
%A Tomasz Ruman
%J International Journal of Chemical Engineering and Applications
%D 2013
%I IACSIT Press
%R 10.7763/ijcea.2013.v4.259
%X The application of new 109 AgNPET nanoparticle surface for analysis of nucleosides and nucleic bases is described along with characterization of 109Ag nanoparticles. The nanoparticles allow laser desorption-ionization mass spectrometry analyses of various low molecular weight (LMW) organic compounds. The new method was used for successful determination of thymidine, 5-fluorouracil, 2¡¯-deoxycytidine, cytidine and 2¡¯-deoxyuridine. The mass determination accuracy was in the 1-3 mDa range which confirms identity of the analyte.
%K Low molecular weight compounds
%K MALDI
%K mass spectrometry
%K matrix-assisted laser desorption-ionization
%K nanoparticles
%K SALDI.
%U http://www.ijcea.org/papers/259-A00004.pdf