%0 Journal Article %T Metabolic responses to the acute ingestion of two commercially available carbonated beverages: A pilot study %A Ron W Mendel %A Jennifer E Hofheins %J Journal of the International Society of Sports Nutrition %D 2007 %I BioMed Central %R 10.1186/1550-2783-4-7 %X After giving informed consent, twenty healthy men and women were randomly assigned to ingest 12 ounces of Celsius£¿ and, on a separate day, 12 ounces of Diet Coke£¿. All subjects completed both trials using a randomized, counterbalanced design. Metabolic rate (via indirect calorimetry) and substrate oxidation (via respiratory exchange ratio) were measured at baseline (pre-ingestion) and at the end of each hour for 3 hours post-ingestion.Two-way ANOVA revealed a significant interaction (p < 0.001) between trials in metabolic rate. Scheffe post-hoc testing indicated that metabolic rate increased by 13.8% (+ 0.6 L/min, p < 0.001) 1 hr post, 14.4% (+0.63 L/min, p < 0.001) 2 hr post, and 8.5% (+0.37 L/min, p < 0.004) 3 hr post Celsius£¿ ingestion. In contrast, small (~4¨C6%) but statistically insignificant increases in metabolic rate were noted following Diet Coke£¿ ingestion. No differences in respiratory exchange ratio were noted between trials.These preliminary findings indicate Celsius£¿ has thermogenic properties when ingested acutely. The effects of repeated, chronic ingestion of Celsius£¿ on body composition are unknown at this time.Over the past few decades, rates of obesity in the United States and many industrialized countries have risen at alarming rates [1]. This is disconcerting given the vast measures that have been taken to counter this effect. For example, the government's Food Guide Pyramid has been overhauled [2]; companies have introduced and/or reformulated their food products to promote lower carbohydrate or lower fat alternatives; schools have begun to ban junk foods from their vending machines; and several professional organizations have published guidelines regarding physical activity levels to promote weight loss [3-6]. Despite these efforts, Americans continue to gain weight [1].Some experts have linked the increase in obesity to the consumption of sugar-containing soft drinks [7,8]. While it is well-known caffeine has a dose-dependent effect on metabo %U http://www.jissn.com/content/4/1/7