%0 Journal Article %T International Society of Sports Nutrition position stand: protein and exercise %A Bill Campbell %A Richard B Kreider %A Tim Ziegenfuss %A Paul La Bounty %A Mike Roberts %A Darren Burke %A Jamie Landis %A Hector Lopez %A Jose Antonio %J Journal of the International Society of Sports Nutrition %D 2007 %I BioMed Central %R 10.1186/1550-2783-4-8 %X Controversy has existed over the safety and effectiveness of protein intake above that currently recommended. Currently, the RDA for protein in healthy adults is 0.8 g/kg body weight per day [1]. The purpose of this recommendation was to account for individual differences in protein metabolism, variations in the biological value of protein, and nitrogen losses in the urine and feces. Many factors need to be considered when determining an optimal amount of dietary protein for exercising individuals. These factors include protein quality, energy intake, carbohydrate intake, mode and intensity of exercise, and the timing of the protein intake [2]. The current recommended level of protein intake (0.8 g/kg/day) is estimated to be sufficient to meet the need of nearly all (97.5%) healthy men and women age 19 years and older. This amount of protein intake may be appropriate for non-exercising individuals, but it is likely not sufficient to offset the oxidation of protein/amino acids during exercise (approximately 1¨C5% of the total energy cost of exercise) nor is it sufficient to provide substrate for lean tissue accretion or for the repair of exercise induced muscle damage [3,4].Protein recommendations are based upon nitrogen balance assessment and amino acid tracer studies. The nitrogen balance technique involves quantifying the total amount of dietary protein that enters the body and the total amount of the nitrogen that is excreted [5]. Nitrogen balance studies may underestimate the amount of protein required for optimal function because these studies do not directly relate to exercise performance. Also, it is possible that protein intake above those levels deemed necessary by nitrogen balance studies may improve exercise performance by enhancing energy utilization or stimulating increases in fat-free mass in exercising individuals [2]. Indeed, an abundance of research indicates that those individuals who engage in physical activity/exercise require higher levels of pro %U http://www.jissn.com/content/4/1/8