%0 Journal Article %T Effect of beta-alanine supplementation on the onset of blood lactate accumulation (OBLA) during treadmill running: Pre/post 2 treatment experimental design %A Thomas Jordan %A Judith Lukaszuk %A Mark Misic %A Josephine Umoren %J Journal of the International Society of Sports Nutrition %D 2010 %I BioMed Central %R 10.1186/1550-2783-7-20 %X Seventeen recreationally-active men (mean ¡À SE 24.9 ¡À 4.7 yrs, 180.6 ¡À 8.9 cm, 79.25 ¡À 9.0 kg) participated in this randomized, double-blind, placebo-controlled pre/post test 2-treatment experimental design. Subjects participated in two incremental treadmill tests before and after 28 days of supplementation with either ¦ÂA (6.0 g¡¤d-1)(¦ÂA, n = 8) or an equivalent dose of Maltodextrin as the Placebo (PL, n = 9). Heart rate, percent heart rate maximum (%HRmax), %VO2max@OBLA (4.0 mmol.L-1 blood lactate concentration) and VO2max (L.min-1) were determined for each treadmill test. Friedman test was used to determine within group differences; and Mann-Whitney was used to determine between group differences for pre and post values (p < 0.05).The ¦ÂA group experienced a significant rightward shift in HR@OBLA beats.min-1 (p < 0.01) pre/post (161.6 ¡À 19.2 to 173.6 ¡À 9.9) but remained unchanged in the PL group (166.8 ¡À 15.8 to 169.6 ¡À 16.1). The %HRmax@OBLA increased (p < 0.05) pre/post in the ¦ÂA group (83.0% ¡À 9.7 to 88.6% ¡À 3.7) versus no change in the PL group (86.3 ¡À % 4.8 to 87.9% ¡À 7.2). The %VO2max@OBLA increased (p < 0.05) in the ¦ÂA group pre/post (69.1 ¡À 11.0 to 75.6 ¡À 10.7) but remained unchanged in the PL group (73.3 ¡À 7.3 to 74.3 ¡À 7.3). VO2max (L.min-1) decreased (p < 0.01) in the ¦ÂA group pre/post (4.57 ¡À 0.8 to 4.31 ¡À 0.8) versus no change in the PL group (4.04 ¡À 0.7 to 4.18 ¡À 0.8). Body mass kg increased (p < 0.05) in the ¦ÂA group pre/post (77.9 ¡À 9.0 to 78.3 ¡À 9.3) while the PL group was unchanged (80.6 ¡À 9.1 to 80.4 ¡À 9.0).¦ÂA supplementation for 28 days enhanced sub-maximal endurance performance by delaying OBLA. However, ¦ÂA supplemented individuals had a reduced aerobic capacity as evidenced by the decrease in VO2max values post supplementation.Running is a popular form of exercise in the United States and for many it is considered a competitive sport. While performance goals can range from simply finishing a race to competition in an Olympic event, it is likely %U http://www.jissn.com/content/7/1/20