%0 Journal Article
%T Lepra Dimorfa Lepromatosa (Borderline Lepromatosa, BL) Dimorphous Lepromatous Leprosy (Borderline Lepromatous, BL
%A M Palombo
%A RE Achenbach
%A GF S芍nchez
%A S Dupuy
%J Revista Argentina de Dermatolog赤a
%D 2012
%I Asociaci車n Argentina de Dermatolog赤a
%X Presentamos un caso de lepra dimorfa lepromatosa, en un hombre austr赤aco radicado en la Argentina desde hace 40 a os, que presentaba placas infiltradas monomorfas y asintom芍ticas en tronco y miembros, sin alteraciones neurol車gicas perif谷ricas evidentes. La biopsia de una de las lesiones demostr車 芍reas de hiperplasia fibrobl芍stica perineural "en catafilas de cebolla", granulomas en contacto focal con la epidermis, con transgresi車n del muro de contenci車n y abundantes bacilos 芍cido-alcohol resistentes, agrupados en la tinci車n para micobacterias. El paciente respondi車 adecuadamente a la terapia con dapsona, rifampicina y clofazimina; sin embargo present車 episodio reacci車nal tipo 1 o "reversal", que requiri車 terapia con prednisona por seis meses. A case of Dimorphous Lepromatous Leprosy in an Austrian man, who had been living in Argentina for the past 40 years is reported. He presented asymptomatic, infiltrated, monomorphous plaques in his trunk and limbs, without peripheral neurologic manifestations. A skin biopsy specimen obtained from an infiltrated lesion on the back, demonstrated areas of perineural fibroblastic hyperplasia "onion-cataphylls like", granulomas contacting epidermis with violation of the Grenz zone and numerous grouped acid-fast bacilli demonstrated with the Ziehl-Neelsen stain. The patient responded well to therapy with dapsone, rifampicine, and clofazamine, but presented a type 1 reaction (reversal reaction) which required a six-months prednisone therapy.
%K Lepra dimorfa lepromatosa
%K Reacci車n tipo 1
%K Borderline lepromatous leprosy
%K Ttype 1 reaction
%U http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-300X2012000100005