%0 Journal Article %T Functional electrical stimulation mediated by iterative learning control and 3D robotics reduces motor impairment in chronic stroke %A Katie L Meadmore %A Ann-Marie Hughes %A Chris T Freeman %A Zhonglun Cai %A Daisy Tong %A Jane H Burridge %A Eric Rogers %J Journal of NeuroEngineering and Rehabilitation %D 2012 %I BioMed Central %R 10.1186/1743-0003-9-32 %X Five hemiparetic, chronic stroke participants with impaired upper limb function attended 18, 1 hour intervention sessions. Participants completed virtual reality tracking tasks whereby they moved their impaired arm to follow a slowly moving sphere along a specified trajectory. To do this, the participants¡¯ arm was supported by a robot. ES, mediated by advanced iterative learning control (ILC) algorithms, was applied to the triceps and anterior deltoid muscles. Each movement was repeated 6 times and ILC adjusted the amount of stimulation applied on each trial to improve accuracy and maximise voluntary effort. Participants completed clinical assessments (Fugl-Meyer, Action Research Arm Test) at baseline and post-intervention, as well as unassisted tracking tasks at the beginning and end of each intervention session. Data were analysed using t-tests and linear regression.From baseline to post-intervention, Fugl-Meyer scores improved, assisted and unassisted tracking performance improved, and the amount of ES required to assist tracking reduced.The concept of minimising support from ES using ILC algorithms was demonstrated. The positive results are promising with respect to reducing upper limb impairments following stroke, however, a larger study is required to confirm this. %K Functional electrical stimulation %K Upper limb %K Stroke rehabilitation %K Iterative learning control %K Robotic support %K Virtual reality %U http://www.jneuroengrehab.com/content/9/1/32/abstract