%0 Journal Article %T Real-time myoelectric control of a multi-fingered hand prosthesis using principal components analysis %A Giulia C Matrone %A Christian Cipriani %A Maria Chiara Carrozza %A Giovanni Magenes %J Journal of NeuroEngineering and Rehabilitation %D 2012 %I BioMed Central %R 10.1186/1743-0003-9-40 %X A clinically viable two DoFs myoelectric controller, exploiting two differential channels, was developed and twelve able-bodied participants, divided in two groups, volunteered to control the hand in simple grasp trials, using forearm myoelectric signals. Task completion rates and times were measured. The first objective (assessed through one group of subjects) was to understand the effectiveness of the approach; i.e., whether it is possible to drive the hand in real-time, with reasonable performance, in different grasps, also taking advantage of the direct visual feedback of the moving hand. The second objective (assessed through a different group) was to investigate the intuitiveness, and therefore to assess statistical differences in the performance throughout three consecutive days.Subjects performed several grasp, transport and release trials with differently shaped objects, by operating the hand with the myoelectric PCA-based controller. Experimental trials showed that the simultaneous use of the two differential channels paradigm was successful.This work demonstrates that the proposed two-DoFs myoelectric controller based on PCA allows to drive in real-time a prosthetic hand emulator into different prehensile patterns with excellent performance. These results open up promising possibilities for the development of intuitive, effective myoelectric hand controllers. %U http://www.jneuroengrehab.com/content/9/1/40/abstract