%0 Journal Article %T Comparative study of tocolytic actions and side effects of Nifedipine versus Ritodrine about the treatment of preterm birth, ¡°Hospital Materno Infantil Germ¨¢n Urquidi¡± (Estudio comparativo de la acci¨®n tocol¨ªtica y efectos adversos del Nifedipino versus Ritodrina, en la amenaza de parto pret¨¦rmino, ¡°Hospital Materno Infantil Germ¨¢n Urquidi¡±) %A Carpio-Deheza Gonzalo %A Vargas-Vega Ana L¨ªa %A Jaillita-Meneses Cristhian %A Flores-Villarroel Cristhian %J Revista M¨¦dico-Cient¨ªfica ¡°Luz y Vida¡± %D 2011 %I Fraternidad Acad¨¦mica Cient¨ªfica Social M¨¦dica "Luz y Vida %X Background: The tocolytic treatment in preterm labor threat hasbecome the basis of management. Its main objective is to delaythe birth. This would permit to complete the scheme of lung maturation.In addition this treatment reduces morbidity and perinatalmortality associated with prematurity.Objective: It is to evaluate the efficacy/effectiveness of Nifedipineand Ritodrine as tocolytic agents in patients with preterm laborthreat in Hospital Materno-Infantil Germ¨¢n Urquidi (HMIGU) duringthe period of September to December 2010.Methods: It is an, analytical, descriptive, retro-prospective, andlongitudinal research where the sample population was: pregnantpatients admitted to HMIGU with the diagnosis of preterm laborthreat, which fulfill the inclusion criteria.Results: Ritodrine presents more general alterations (headache,nausea and vomiting), the relationship was 1.5-4:1 versus Nifedipine.Talking about hypotension as side effect, Ritodrine presentedmore cases in a ratio of 1.7:1 to Nifedipine. Finally, in terms of sideeffects on the fetus. It was observed variations in fetal heart rate.there was a significant tachycardia of more than 10-20 beats per minute compared to baseline. This happened in 25% of women treatedwith Ritodrine versus 10% of women treated with Nifedipine.Conclusion: Nifedipine proved to be an effective utero inhibitiondrug between 24-34 weeks, presenting minimal side effects in patientswithout premature rupture of membranes, nor associated disease.In addition, it had a very good cost-benefit ratio respect toRitodrine. -RESUMEN: Introducci¨®n: El tratamiento tocol¨ªtico en Amenaza de Parto Pret¨¦rmino, se ha convertido en la piedra angular de su manejo, dondeel objetivo principal es retrasar el nacimiento, lo cual permitir¨ªaadministrar un esquema completo de maduraci¨®n pulmonar, adem¨¢sde disminuir la morbi-mortalidad perinatal asociada a la prematurez.Objetivo: Evaluar la eficacia/efectividad del Nifedipino versus Ritodrina como agentes tocoliticos, en pacientes con diagn¨®stico deAmenaza de Parto Pret¨¦rmino del Hospital Materno-Infantil Germ¨¢nUrquidi (HMIGU), durante el periodo de septiembre a diciembrede 2010.Material y M¨¦todos: Es una investigaci¨®n, anal¨ªtica-descriptiva,retro-prospectiva, longitudinal donde la muestra fue: pacientes embarazadas, internadas en el HMIGU, con el Diagn¨®stico de Amenazade Parto Pret¨¦rmino, que cumplan con los criterios de inclusi¨®n.Resultados: La Ritodrina presento m¨¢s alteraciones generales (cefalea,n¨¢useas y v¨®mitos), en una relaci¨®n que fue de 1.5-4:1 versusNifedipino. En cuanto al papel de hipotensor, se lo %K Tocolytic Actions %K Nifedipine versus Ritodrine %K Teatment of preterm birth. %U https://docs.google.com/viewer?a=v&pid=sites&srcid=ZGVmYXVsdGRvbWFpbnxyZXZtZWRpY29jaWVudGlmaWNhbHV6eXZpZGF8Z3g6N2Q0MDYwYTc1NDgwNGEwMA