%0 Journal Article
%T Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment
%A Tzu-Chun Liao
%A J. Andrew Yeh
%J International Journal of Automation and Smart Technology
%D 2012
%I Chinese Institute of Automation Engineers, Taiwan Smart Living Space Association
%R 10.5875/ausmt.v2i1.116
%X A new kind of microdroplet-based biological protein sensor is presented. The sensor was made by placing silicon oil on gold film with a self-assembled monolayer (SAM). The surface tension dominates the sensitivity of the sensor. Using mercaptoundecanoic acid (11-MUA) as the sensor¡¯s SAM layer, the sensor can detect 0.5 mg/ml, 20 ¦̀g/ml, and 0.4 ¦̀g/ml bovine serum albumin (BSA) protein solutions in a control volume of 0.5ml. The sensor¡¯s reaction time for concentrations of 0.5 mg/ml, 20 ¦̀g/ml, and 0.4¦̀g/ml protein solutions was 15, 60 and 120 minutes, respectively. As the size of microdroplet decreased, the change of contact angle increased.
%K microdroplet
%K protein sensor
%K self-assembled monolayer (SAM)
%U http://www.ausmt.org/index.php/AUSMT/article/view/116