%0 Journal Article
%T Correlaci¨®n entre s¨ªntomas de reflujo gastroesof¨¢gico y resultados de la pHmetr¨ªa de 24 horas en pacientes con estudio endosc¨®pico normal o levemente alterado Relationship between gastroesophageal reflux symptoms and 24 h esophageal pH measurement in patients with normal or minimally abnormal upper endoscopies
%A Attila Csendes J
%A Guillermo Rencoret P
%A Marcelo Beltr¨¢n S
%A Gladys Smok S
%J Revista m¨¦dica de Chile
%D 2004
%I Sociedad M¨¦dica de Santiago
%X Heartburn and regurgitation are considered highly specific symptoms of gastroesophageal reflux. A considerable number of patients with these symptoms do not have endoscopic signs of esophagitis. Aim: To study the relationship between gastroesophageal reflux symptoms and 24 h esophageal pH mesurement in patients with normal or near normal endoscopic findings. Patients and methods: One hundred eighty six patients with persistent reflux symptoms and absence of severe endoscopic esophagitis were studied. Pathological studies of esophageal biopsies, manometry and 24 h esophageal pH measurements were performed in all. Results: Abnormal acid reflux was found in 131 patients (70%). No differences in the frequency of symptoms, gender or pathologic findings were observed between patients with or without abnormal acid reflux. However, a higher frequency of esophageal erosions and a lower resting pressure of the inferior sphincter of the esophagus was observed in patients with abnormal acid reflux. Conclusions: Thirty percent of patients with heartburn and regurgitation did not have abnormal acid reflux. Therefore, these symptoms are not specific for gastroesophageal reflux (Rev M¨¦d Chile 2004; 132: 19-25).
%K Esophagoscopy
%K Esophagitis
%K peptic
%K Gastroesophageal reflux
%U http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000100003