%0 Journal Article %T Endoscopic application of n-butyl-2-cyanoacrylate on esophagojejunal anastomotic leak: a case report %A Manousos-Georgios Pramateftakis %A Georgios Vrakas %A Ioannis Kanellos %A Ioannis Mantzoros %A Stamatis Angelopoulos %A Efthymios Eleftheriades %A Charalampos Lazarides %J Journal of Medical Case Reports %D 2011 %I BioMed Central %R 10.1186/1752-1947-5-96 %X This report describes a case of a 68-year-old Caucasian man who underwent surgery for gastric cancer. He underwent total gastrectomy and esophagojejunal anastomosis with Roux-en-Y anastomosis plus transverse colectomy. An anastomotic leak was treated conservatively at first for a total of three weeks. However, the leak persisted; therefore, the decision was made to apply topical endoscopic n-butyl-2-cyanoacrylate.The endoscopic application of n-butyl-2-cyanoacrylate alone can be used successfully to treat esophagojejunal anastomotic leakage.Esophagojejunal anastomotic leakage is a serious complication following total gastrectomy. Studies report a frequency between 4% and 16% [1-5]. Once a leak is identified, the surgeon has to decide whether to follow conservative or surgical treatment. The conservative treatment remains drainage, parenteral nutrition and antibiotics. The endoscopic application of several tissue adhesives, such as Human Fibrin Glue can seal the anastomotic leak site. On the basis of the available bibliography, no studies to date have reported the use of n-butyl-2-cyanoacrylate for this purpose. The aim of our study is to present the case of an esophagojejunal anastomotic leak that was treated successfully with the topical endoscopic application of n-butyl-2-cyanoacrylate.We present the case of a 68-year-old Caucasian man who underwent surgery for gastric cancer. The tumor was arising from the pylorus and was extending higher up to the lesser curvature of the stomach. The computed tomography (CT) scan revealed infiltration of the transverse mesocolon. Therefore, the patient underwent total gastrectomy and esophagojejunal anastomosis (EEA 25 circular stapler) with Roux-en-Y anastomosis plus transverse colectomy. Both the jejunojejunal and colon anastomoses were performed in one layer with interrupted 3-0 Vicryl sutures. On the seventh postoperative day, we tested the anastomosis with radiographic studies using gastrograffin, which revealed a leak from %U http://www.jmedicalcasereports.com/content/5/1/96