%0 Journal Article
%T Frequency and characteristics of metabolic syndrome in patients with symptomatic carotid atherosclerosis Frecuencia y caracter¨ªsticas del s¨ªndrome metab¨®lico en pacientes con estenosis carot¨ªdea sintom¨¢tica
%A Milos Maksimovic
%A Hristina Vlajinac
%A Djordje Radak
%A Jadranka Maksimovic
%J Revista m¨¦dica de Chile
%D 2009
%I Sociedad M¨¦dica de Santiago
%X Background: Metabolic syndrome (MetS) is associated with increased risk of carotid atherosclerosis. Aim: To estimate the frequency of MetS in patients with symptomatic carotid atherosclerotic disease, and to compare clinical, biochemical and ultrasonographic characteristics of patients with and without MetS. Material and methods: Cross-sectional study of 657 consecutive patients (412 males) with symptomatic carotid atherosclerotic disease. Carotid atherosclerosis was estimated by high resolution B-mode ultrasonography. National Cholesterol Education Program (NCEP) M criteria were used for estimation of MetS. Results: Metabolic syndrome was present in 55.6% of studied patients. Among patients with metabolic syndrome there was a significantly higher proportion of women, and mean values ofbody weight, body mass index, waist circumference, percentage of body fat, systolic and diastolic blood pressure, serum triglycerides, total cholesterol and glucose were significantly higher. Mean values of high density lipoprotein cholesterol and alcohol consumption were significantly lower in patients with MetS. No differences between patients with or without MetS, were observed for age, smoking, mean values of low density lipoprotein cholesterol, high sensitive C-reactive protein and fibrinogen, and for degree of carotidstenosis or severity of clinical manifestations. Conclusion: Half of these patients with carotid stenosis have features of the metabolic syndrome. Antecedentes: El s¨ªndrome metab¨®lico se asocia a un mayor riesgo de ateroesclerosis carot¨ªdea. Objetivo: Evaluar la frecuencia de s¨ªndrome metab¨®lico en pacientes con ateroesclerosis carot¨ªdea sintom¨¢tica y comparar las caracter¨ªsticas cl¨ªnicas, bioqu¨ªmicas y ultrasonogr¨¢ficas en pacientes con y sin s¨ªndrome metab¨®lico. Material y m¨¦todo: Estudio transversal de 657 pacientes consecutivos (412 varones) con ateroesclerosis carot¨ªdea sintom¨¢tica. El s¨ªndrome metab¨®lico fue diagnosticado de acuerdo a los criterios del National Cholesterol Education Program (NCEP) III. la ateroesclerosis carot¨ªdea se investig¨® mediante ultrasonograf¨ªa de alta resoluci¨®n modo B. Resultados: Se diagnostic¨® s¨ªndrome metab¨®lico en 55.6% de los pacientes estudiados. Entre los sujetos portadores del s¨ªndrome hab¨ªa una mayor proporci¨®n de mujeres y el peso, ¨ªndice de masa corporal, circunferencia de cintura, porcentaje de grasa corporal, presi¨®n arterial sist¨®lica y diast¨®lica y niveles s¨¦ricos de triglic¨¦ridos, colesterol total y glicemia fueron mayores. los valores promedio de colesterol HDI y de consumo de alcohol fueron significativa
%K Carotid artery diseases
%K High density lipoprotein cholesterol
%K Metabolic syndrome
%U http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000300002