%0 Journal Article
%T Oncocytic carcinoma of the parotid gland with late cervical lymph node metastases: a case report
%A Lorena Gallego
%A Luis Garc¨ªa-Consuegra
%A Eduardo Fuente
%A Nicol¨¢s Calvo
%A Luis Junquera
%J Journal of Medical Case Reports
%D 2011
%I BioMed Central
%R 10.1186/1752-1947-5-11
%X We report a case of oncocytic carcinoma arising in the parotid gland of a 65-year-old Caucasian man. Our patient initially underwent left superficial parotidectomy, including the removal of the mass. A close follow-up was made, and four years after first surgery cervical lymph node metastases were confirmed. Therefore, a complete parotidectomy and radical neck dissections were performed. There were no complications and no sign of recurrence after six months of follow-up.Oncocytic carcinoma is an extremely rare malignancy in the salivary glands. Prophylactic neck dissection may be indicated for tumors larger than 2 cm in diameter (our patient's tumor was 2.5 cm at its greatest diameter). The clinical course of our patient, with the appearance of cervical lymph node metastases after four years of follow-up, supports this approach. Further investigation of the prognosis and correct treatment of patients with oncocytic carcinoma are required as more cases are reported.Oncocytic carcinoma (OC) is an unusual proliferation of cytomorphologically malignant oncocytes and adenocarcinomatous architecture phenotypes mainly found in glandular tissue [1]. The terms oncocytic carcinoma, oncocytic adenocarcinoma, malignant oncocytoma and malignant oxyphilic adenoma are synonymous. Its malignant nature is distinguished from oncocytoma by abnormal morphological features and infiltrative growth [2]. Necrosis, peri-neural spread, pleomorphism, intra-vascular invasion, and distant metastasis to the cervical lymph nodes, kidneys, lungs, and mediastinum are the main features of this high-grade malignant tumor [1].This tumor represents 5% of all oncocytic salivary gland neoplasms and less than 1% of all salivary gland tumors [3]. OC may occur in many sites in addition to the salivary glands, including the nasal and thoracic cavities, ovary, kidney, thyroid gland, breast and parathyroid. The majority of OC cases have occurred in the parotid glands, but tumors that involved the submandibular
%U http://www.jmedicalcasereports.com/content/5/1/11