%0 Journal Article %T Stroke with neuropsychiatric sequelae after cannabis use in a man: a case report %A Benoit Trojak %A St¨¦phanie Leclerq %A Vincent Meille %A Catia Khoumri %A Jean-Christophe Chauvet-Gelinier %A Maurice Giroud %A Bernard Bonin %A Andr¨¦ Gisselmann %J Journal of Medical Case Reports %D 2011 %I BioMed Central %R 10.1186/1752-1947-5-264 %X A 24-year-old Caucasian man was discovered in a deeply comatose non-reactive state after cannabis use. A magnetic resonance imaging scan of his brain showed bilateral multiple ischemic infarcts. The patient remained deeply comatose for four days, after which time he developed other behavioral impairments and recurrent seizures.Stroke related to cannabis use can be followed by severe neuropsychiatric sequelae. Concomitant alcohol intoxication is essential neither to the occurrence of this neurologic event nor to its severity.Over the past few years, ischemic stroke associated with cannabis use has been reported in the literature. Typically, this accident concerns young, frequent cannabis smokers and usually occurs following cannabis consumption with simultaneous intake of alcohol, which is also thought to play a role in the cerebrovascular event [1]. In most case reports, the outcome of the neurovascular event was favorable and the patients rapidly recovered from stroke within hours or a few days.Here we report the case of a young man who presented to our hospital with stroke that led to four days of deep coma, followed by neuropsychiatric sequelae. Moreover, this stroke occurred in the absence of alcohol intoxication.A 24-year-old Caucasian French man with no specific medical history was discovered in a deeply comatose, non-reactive state approximately 12 hours after he had fallen from a first-floor balcony under unknown circumstances. His blood pressure was 110/70 mmHg. During the physical examination, the mobile medical emergency team observed conjugate deviation of the eyes and concluded that the patient was having seizures. He was immediately treated with intravenous diazepam 10 mg, which had no impact on his level of consciousness, so he was intubated while on his way to our hospital.The initial medical check-up conducted on admission to the medical intensive care unit did not reveal any biological anomalies related to his coma (electrolytes, glucose, ammonia l %U http://www.jmedicalcasereports.com/content/5/1/264