%0 Journal Article %T Salmonella enterica ssp. arizonae infection in a 43-year-old Italian man with hypoglobulinemia: a case report and review of the literature %A Stefano Di Bella %A Alessandro Capone %A Eugenio Bordi %A Emma Johnson %A Maria Musso %A Simone Topino %A Pasquale Noto %A Nicola Petrosillo %J Journal of Medical Case Reports %D 2011 %I BioMed Central %R 10.1186/1752-1947-5-323 %X We describe the case of a 43-year-old Caucasian Italian man with hypoglobulinemia who presented to our hospital with sepsis and diarrhea. A stool culture yielded S. enterica ssp. arizonae. Our patient was treated with oral ciprofloxacin and made a full recovery. We also present a review of the cases of S. enterica ssp. arizonae infections previously reported in Europe.The majority of infections from S. enterica ssp. arizonae occur in patients who are immunocompromised. Data from the literature suggests that it may be difficult to eradicate the bacteria and thus, prolonged antibiotic courses are often used. It would be advisable for clinicians to investigate for pre-existing immune dysfunction if S. enterica ssp. arizonae is isolated. In Italy, although there have only been a few cases, the likely route of transmission remains unclear and requires further surveillance.Salmonella enterica ssp. arizonae is an uncommon human pathogen with serious human infections reported in hosts with impaired immune function. S. enterica ssp. arizonae infections have been well described in patients resident within the southwestern part of the US and in Mexico, whereas in Europe only a few cases have been reported. Patients with this infection usually have a history of contact with reptiles or travel abroad.We present a case report of S. enterica ssp. arizonae infection in an adult patient with hypoglobulinemia and literature review of previous cases.A 43-year-old Caucasian Italian man was admitted to our hospital presenting with fever, mucoid diarrhea and abdominal cramps for the past 20 days. Associated symptoms included malaise and a 5 kg weight loss during this time. During the previous week he had taken paromomycin along with bacitracin and neomycin, with no clinical improvement.He had been diagnosed with Hodgkin's disease 15 years previously, which was treated with chemotherapy and autologous bone marrow transplant. Three years ago he had experienced a relapse, which was treated %U http://www.jmedicalcasereports.com/content/5/1/323