%0 Journal Article
%T Hemangioendotelioma epitelioide y fusiforme de ganglio linf¨¢tico: Caso cl¨ªnico Spindle and epithelioid hemangio-endothelioma of the lymph node: Report of one case
%A Alejandro Avil¨¦s-Salas
%A Jos¨¦ Cruz Torres-Lucatero
%A Ximena Fernandez-Soto
%A Myrna Candelaria-Hern¨¢ndez
%J Revista m¨¦dica de Chile
%D 2013
%I Sociedad M¨¦dica de Santiago
%X Background: Primary vascular tumors of lymph nodes are extremely rare with the exception of AlDS-related Kaposi's sarcoma. The diagnosis of epithelioid hemangio-endothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular nature and it may be overlooked when it appears as a primary tumor of lymph nodes. Spindle and epithelioid hemangio-endothelioma (SEH) is considered to be a variant of EH, which has been reported to occur exclusively in lymph nodes and the spleen. We report a 70-year-old male with chronic lymphocytic leukemia (CLL) and left cervical lymphadenopathy. An excisional biopsy was performed, and microscopically the lymph node showed effacement of nodal architecture by a tumor composed of spindle cells disposed in intersecting fascicles, and characterized by abundant eosinophilic cytoplasm, elongated nuclei and conspicuous nucleoli. A second population of cells had an epithelioid appearance with intracyto-plasmic vacuoles containing red blood cells. lmmunohistochemically, the tumor cells were positive for CD31 and CD34. The final diagnosis was SEH of the lymph node.
%K Hemangio-endothelioma
%K epithelioid
%K Lymph nodes
%K Vascular neoplasms
%U http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200017