%0 Journal Article
%T Thyroglossal duct cyst carcinoma with concurrent thyroid carcinoma: a case report
%A Vittorio Gebbia
%A Carlo Di Gregorio
%A Marco Attard
%J Journal of Medical Case Reports
%D 2008
%I BioMed Central
%R 10.1186/1752-1947-2-132
%X A further case of thyroglossal duct carcinoma and concurrent thyroid carcinoma with locoregional lymph node metastases affecting a 40-year-old woman followed up for 4 years is presented and discussed.Sistrunk's surgical technique must always be the initial treatment, but in case of carcinoma further surgery, that is, thyroidectomy with or without lymph node dissection, and treatment with radioactive iodine have to be considered according to the microscopic and clinical findings. Accurate pre-operative clinical and radiological evaluation should be performed in order to plan surgical strategy.A thyroglossal duct cyst is a developmental abnormality of the thyroid gland, which often manifests clinically as a mass along the thyroglossal tract [1]. The thyroglossal tract is a remnant of the thyroid development. During its descent, in fact, the thyroid gland connects to the base of the tongue through this duct, which later involutes and disappears. Sometimes it may persist and undergo dilatation responsible for thyroglossal duct cyst formation. The presence of ectopic thyroid tissue in a thyroglossal duct cyst varies from 1.5% to 45% of cases [1] and can be explained on the basis of the gland embryology [2].Carcinoma arising in this tract is an uncommon clinico-pathologic entity [3,4]. The median age at presentation is 40 years [3,4] and females are affected slightly more often than males with a 3:2 ratio. The peak incidence for women and men is in the third and sixth decades, respectively. Overall age and sex distribution is similar to that of patients with thyroid carcinoma. Regional lymph node metastases of papillary carcinomas in thyroglossal cysts occur much less frequently than in primary cancer of the thyroid, with incidence of less than 8% of cases [1]. Moreover, papillary thyroglossal duct carcinoma (TDC) seldom shows distant metastases and its prognosis is similar to that of the thyroid papillary carcinomas.Although a few cases of follicular, mixed follicular-pa
%U http://www.jmedicalcasereports.com/content/2/1/132