%0 Journal Article
%T The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature
%A Satoko Yamamoto
%A Takao Asanuma
%A Toshihisa Takagi
%A Ken Ichiro Fukuda
%J Comparative and Functional Genomics
%D 2004
%I Hindawi Publishing Corporation
%R 10.1002/cfg.432
%X In general, it is not easy to specify a single sequence identity for each molecule name that appears in a pathway in the scientific literature. A molecule name may stand for concepts of various granularities, from concrete objects such as H-Ras and ERK1 to abstract concepts or categories such as Ras and MAPK. Typically, the relations among molecule names derive a hierarchical structure; without a proper way to handle this knowledge, it becomes ever more difficult to develop a reliable pathway database. This paper describes an ontology that is designed to annotate molecules in the scientific literature on signal transduction pathways.
%U http://www.hindawi.com/journals/cfg/2004/439679/abs/