%0 Journal Article %T Accelerated CMR using zonal, parallel and prior knowledge driven imaging methods %A Sebastian Kozerke %A Sven Plein %J Journal of Cardiovascular Magnetic Resonance %D 2008 %I BioMed Central %R 10.1186/1532-429x-10-29 %X With all acceleration techniques, careful consideration of the limits and the trade-off between acceleration and occurrence of artifacts that may arise if these limits are breached is required. In parallel imaging the spatially varying noise has to be considered when measuring contrast- and signal-to-noise ratios. Also, temporal fidelity in images reconstructed with prior knowledge driven methods has to be studied carefully.The use of Magnetic Resonance (MR) methods in the cardiovascular realm continues to gain impact. A number of clinical indications have already been identified with Class I rating, including the assessment of global ventricular function and mass and the detection of acute and chronic myocardial infarction and myocardial scar [1]. A range of further applications have been indicated [2]. For example, recent results from a multi-vendor, multi-center clinical trial showed high diagnostic performance of myocardial perfusion MR imaging [3] compared with nuclear scintigraphy, suggesting that this method will have an important future role in clinical practice.The technological development in cardiovascular MR (CMR) has been enormous with considerable innovations refining existing or even enabling new applications. A key driving factor for this innovation process has been the challenge to image in the presence of considerable object motion as it is found in the heart. Satisfying competing demands on total scan duration, image quality and spatiotemporal resolution has been a core motivation. With many CMR applications being performed during a breathhold, improving spatiotemporal resolution for a given, tolerable scan duration is of great importance. Improved spatiotemporal resolution allows discerning finer details of object structure and dynamics. Also, on a fundamental level, spatial and temporal resolutions determine image quality as the degree of partial volume artifacts, image fidelity of dynamic features and motion induced image distortions are affect %U http://jcmr-online.com/content/10/1/29