%0 Journal Article
%T Impact of patient-prosthesis mismatch on 30-day outcomes in young and middle-aged patients undergoing aortic valve replacement
%A Daniel Hern¨¢ndez-Vaquero
%A Juan C Llosa
%A Roc¨ªo D¨ªaz
%A Zain Khalpey
%A Carlos Morales
%A Rub¨¦n ¨¢lvarez
%A Jose L¨®pez
%A Francisco Boye
%J Journal of Cardiothoracic Surgery
%D 2012
%I BioMed Central
%R 10.1186/1749-8090-7-46
%X We analyzed our single center experience in all patients <70£¿years undergoing first-time isolated aortic valve replacement for severe stenosis in our center from September 2007 to September 2011. PPM was defined as an indexed effective orifice area£¿¡Ü£¿0,85£¿cm2/m2. The influence of PPM on early mortality and postoperative complications was studied using propensity score analysis. Follow up at 30 postoperative days was 100% complete.Of 199 patients studied, 61 (30,7%) had some degree of PPM. PPM was associated with an increased postoperative mortality (OR£¿=£¿8,71; 95% CI£¿=£¿1,67¨C45,29; p£¿=£¿0,04) and major postoperative complications (OR£¿=£¿2,96; CI£¿=£¿1,03¨C8,55; p£¿=£¿0,044). However, no association between PPM and prolonged hospital or ICU stay was demonstrated.Moderate PPM is a common finding in young and middle-aged patients undergoing surgery for aortic valve replacement due to severe stenosis. In addition, its influence on early outcomes may be relevant.
%K Patient-prosthesis mismatch
%K Severe aortic stenosis
%U http://www.cardiothoracicsurgery.org/content/7/1/46/abstract