%0 Journal Article
%T Anti-glomerular basement membrane disease, ulcerative colitis, and primary sclerosing cholangitis: link or co-incidence?
%A Emilie Pin£¿on
%A Guillaume Bouguen
%A Guillaume Coiffier
%A Joseph Rivalan
%J Nephrology Reviews
%D 2010
%I 
%R 10.4081/nr.2010.e10
%X Ulcerative colitis, primary sclerosing cholangitis, and anti-glomerular basement membrane disease (anti-GBM) are three rare immune diseases with incompletely understood pathogenic mechanisms. We describe here the case of a 29-year-old man with ulcerative colitis and primary sclerosing cholang-itis who, eight years later, developed anti-GBM disease with destruction of all glomeruli leading to end-stage kidney disease. Association of these three immune diseases in the same patient has never been described. Because HLA-mediated susceptibility cannot be incriminated completely in our case, we hypothesize that environmental factors or previous immunosuppressive treatment used might be the link.
%U http://www.pagepress.org/journals/index.php/nr/article/view/1817