%0 Journal Article
%T Protein Functionalized Nanodiamond Arrays
%A Liu YL
%A Sun KW
%J Nanoscale Research Letters
%D 2010
%I Springer
%X Various nanoscale elements are currently being explored for bio-applications, such as in bio-images, bio-detection, and bio-sensors. Among them, nanodiamonds possess remarkable features such as low bio-cytotoxicity, good optical property in fluorescent and Raman spectra, and good photostability for bio-applications. In this work, we devise techniques to position functionalized nanodiamonds on self-assembled monolayer (SAMs) arrays adsorbed on silicon and ITO substrates surface using electron beam lithography techniques. The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically. The optical properties of the nanodiamond-protein complex arrays were characterized by a high throughput confocal microscope. The synthesized nanodiamond-lysozyme complex arrays were found to still retain their functionality in interacting with E. coli.
%K Nanodiamond
%K Biosensor
%K Self-assembled monolayer
%U http://dx.doi.org/10.1007/s11671-010-9600-7