%0 Journal Article %T Progressive fibrosis of the quadriceps muscle FIBROSIS PROGRESIVA DEL CU芍DRICEPS %A Enrique Vergara-Amador %A Jorge Andr谷s Largo Gonz芍lez %J Revista Facultad de Medicina de la Universidad Nacional de Colombia %D 2011 %I Universidad Nacional de Colombia %X Background. Fibrosis of the quadriceps in children is a frequently reported pathology which is associated with antibiotics having been injected into the thigh. This study presents a series of patients having a common background of having had a single pentavalent vaccine dose or injectable vitamin K and presenting progressive fibrosis of the quadriceps muscle. Materials and methods. Seven children were found who had progressive unilateral retraction of the knee. Six of them had a background of a single dose of vaccine having been given when they were four months old, suffering muscle contractions/spasms 4 to 8 weeks after the application; one child had been given vitamin K when born. Results. Magnetic resonance revealed alterations in the intermediate vastus medialis obliquus (VMO) without intra-articular pathology. Average age when surgery was performed was 18 months (16-20 month range) and preoperational flexion was 26∼ (20∼-30∼). The quadriceps central tendon was stretched, without quadriceplasy, flexion being improved to 90∼ in 1 case and 100∼ to 120∼ in the remaining ones. Minimum follow-up lasted six months, average post-operational flexion being 109∼ (90∼-120∼). Discussion. The intermediate VMO has been used for applying drugs. There is evidence that this muscular portion has poor perfusion in children. The fibrosis's physiopathology is still not exactly known. Many children are given a poor diagnosis, this being confused with articular pathologies so that they wrongly receive other types of surgery. Antecedentes. La fibrosis del cu芍driceps en ni os es una patolog赤a reportada con frecuencia y asociada a la aplicaci車n de antibi車ticos en el muslo. Este estudio presenta una serie de pacientes que ten赤an como antecedente com迆n la aplicaci車n de una dosis 迆nica de la vacuna pentavalente o de vitamina K y presentaron fibrosis del cu芍driceps progresivo. Material y m谷todos. Se encontraron siete ni os con retracci車n progresiva unilateral de la rodilla. Seis ten赤an antecedente de la aplicaci車n de una sola dosis de vacuna a los cuatro meses de edad con contractura entre la 4a y 8a. semana posterior de la aplicaci車n, y un ni o la aplicaci車n de vitamina K al nacer. Resultados. La resonancia magn谷tica mostr車 alteraciones en el vasto intermedio sin patolog赤a intraarticular. El promedio de edad de la cirug赤a fue de 18 meses (16-20 meses) y la flexi車n preoperatoria fue de 26∼ (20∼-30∼). Se realiz車 alargamiento del tend車n central del cu芍driceps, sin cuadriceplastia mejorando la flexi車n a 90∼ en 1 caso y los restantes entre 100∼ y 120∼. El seguimiento m赤nimo fue de s %K fibrosis %K contractura %K m迆sculo cu芍driceps %K vacuna %K fibrosis %K contracture %K quadriceps muscle %K vaccines %U http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-00112011000200005