%0 Journal Article
%T Lignans and an Abundant flavone glycoside with Free-Radical Scavenging Activity from the Roots of the Endemic Species Stachys mialhesi de No¨¦
%A Souheila Laggoune
%A Ignacio Brouard
%A Francisco Leon
%A Claude-Alain Calliste
%J Records of Natural Products
%D 2011
%I ACG Publications
%X Two sterols, stigmasterol (1) and ¦Â-sitosterol (2), two lignans, (+)-sesamin (3), new for the genus Stachys and (¡À)-paulownia (4), new in the Lamiaceae family, reported for the second time from a natural source, and one acetylated flavone glycoside isoscutellarein-7-O-(2''-O-6'''-O-acetyl-¦Â-D-allopyranosyl-¦Â-D-glucopyranoside (5), were isolated from the roots of Stachys mialhesi de No¨¦. Surprisingly, 3g of compound 5 are gathered from 5g of roots extract. The structures of compounds 1-5 were established on the basis of physical and spectroscopic analysis, and by comparison with the literature data. The free-radical-scavenging property of compound 5 was evaluated by the use of the ESR method in order to visualize the inhibition of the 1,1-diphenyl-2-1picrylhydrazyl (DPPH) free radical.
%K Stachys mialhesi
%K Lamiaceae
%K lignans
%K free radical scavenging activity
%K ESR.
%U http://www.acgpubs.org/RNP/2011/Volume%205/Issue%201/30-RNP-1008-287.pdf