%0 Journal Article
%T Antimalarial, Anticancer, Antimicrobial Activities and Chemical Constituents of Essential Oil from the Aerial Parts of Cyperus kyllingia Endl.
%A Sorachai Khamsan
%A Boonsom Liawruangrath
%A Saisunee Liawruangrath
%A Aphiwat Teerawutkulrag
%J Records of Natural Products
%D 2011
%I ACG Publications
%X The chemical constituents of the essential oil from Cyperus kyllingia Endl. were analyzed by a GC, GC-MS. Twenty-three compounds were identified, accounting for 93.75% of the total oil that consisted mainly of oxygenated sesquiterpenes (53.52%), particularly sesquiterpene hydrocarbons (38.97%), and carboxylic acid (1.26%). The most representative compounds were a -cadinol (19.32 %), caryophyllene oxide (12.17%), a -muurolol (11.58 %), a -humulene (9.85%), and a -atlantone (6.07%). The oil showed significant activities against Plasmodium falcipalum (K1, multi drug resistant strain) and NCI-H187 (Small Cell Lung Cancer) with the IC 50 values of 7.52 and 7.72 ¦Ìg/mL, respectively. The oilexhibited highly active against Staphylococcus aureus ATCC25923 and moderately active against Escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27553, Aspergillus flavus and Candida albicans.
%K Cyperus kyllingia Endl.
%K essential oil
%K antimalarial activity
%K anticancer activity
%K antimicrobial activity
%U http://www.acgpubs.org/RNP/2011/Volume%205/Issue%201/43-RNP-1008-299.pdf