%0 Journal Article
%T Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential Oil of Salvia chrysophylla Staph
%A Mehmet Emin Duru
%A G¨¹lsen Tel
%A Mehmet £¿zt¨¹rk
%A Mansur Harmandar
%J Records of Natural Products
%D 2012
%I ACG Publications
%X The essential oil from the aerial parts of Salvia chrysophylla Staph (Lamiaceae), endemic to Turkey, was investigated by using GC and GC-MS. Fifty-four of 55 components, represented 99.52% of the total oil were identified. The major components of the essential oil were found to be ¦Á-terpinenyl acetate (36.31%), ¦Â-caryophyllene (15.29%), linalool (8.12%) and ¦Â-elemene (4.26%). The antioxidant activity of the oil was investigated by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ¦Â-carotene/linoleic acid tests. Anticholinesterase activity was screened against acetylcholinesterase and butyrylcholinesterase which are the chief enzymes of Alzheimer¡¯s diseases. The essential oil showed weak antioxidant activity. However, at 1 mg/mL concentration, the essential oil exhibited mild acetylcholinesterase (52.5¡À2.0%) and modarate butyrylcholinesterase (76.5¡À2.7%) inhibitory activity.
%K Salvia chrysophylla
%K essential oil
%K GC and GC-MS
%K antioxidant activity
%K anticholinesterase activity
%U http://www.acgpubs.org/RNP/2012/Volume%206/Issue%201/26-RNP-1104-602-.pdf