%0 Journal Article
%T Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
%A Marius Mihasan
%A Vlad Artenie
%J Analele £¿tiin£¿ifice Ale Universit£¿£¿ii Alexandru Ioan Cuza din Ia£¿i,Sectiunea II A : Genetica si Biologie Moleculara
%D 2008
%I Alexandru Ioan Cuza University of Iasi
%X The pAO1 megaplasmid of Arthrobacter nicotinovorans encodes two different pathways: one for nicotine metabolism and an putative sugar catabolic pathway. Using computational methods, the preferences for sugar of an oxidoreductase from the megaplasmid was addressed. The experimental and modeling data showed that the enzyme is tetrameric, has an ligand binding place close to the EKP conserved sequence and might prefer as substrate ketohexoses.
%U http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/708