%0 Journal Article
%T Factors influencing receptivity to future screening options for pancreatic cancer in those with and without pancreatic cancer family history
%A Carmen M Radecki Breitkopf
%A Pamela S Sinicrope
%A Kari G Rabe
%A Tabetha A Brockman
%A Christi A Patten
%A Robert R McWilliams
%A Shawna L Ehlers
%A Gloria M Petersen
%J Hereditary Cancer in Clinical Practice
%D 2012
%I BioMed Central
%R 10.1186/1897-4287-10-8
%X At-risk family members and primary care controls were surveyed regarding perceived PC risk, PC worry/concern, attitude toward cancer screening, screening test accuracy, and intentions regarding PC screening via blood testing or more invasive endoscopic ultrasound (EUS).PC family members reported greater perceived risk of PC than controls (54% vs. 6%, respectively, p£¿<£¿0.0001). PC family members also reported higher levels of PC worry/concern than controls (p£¿<£¿0.0001), although 19% of PC family members indicated they were ¡°not at all concerned¡± about getting PC. PC family members indicated greater acceptance of a false-negative result on a PC screening test relative to controls (12% vs. 8%, p£¿=£¿0.02). Both groups reported high (>89%) receptivity to the potential PC screening options presented, though receptivity was greater among PC family members as compared to controls (p£¿<£¿0.0001) for EUS. In multivariable analyses, degree of PC concern (p£¿<£¿0.0001) was associated with intention to screen for PC by blood test and EUS, while perceived PC risk was associated with likelihood of undergoing EUS only (p£¿<£¿0.0001).Receptivity to screening options for PC appears high. Clinicians should address behavioral and genetic risk factors for PC and foster appropriate concern regarding PC risk among at-risk individuals.
%K Pancreatic cancer
%K Health behavior
%K Perceived risk
%K Screening intentions
%U http://www.hccpjournal.com/content/10/1/8/abstract