%0 Journal Article
%T Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
%A MOREIRA DAVYSON L.
%A SOUZA PATR¨ªCIA O.
%A KAPLAN MARIA AUXILIADORA C.
%A PEREIRA NUNO A.
%J Anais da Academia Brasileira de Ci¨ºncias
%D 2001
%I Academia Brasileira de Ci¨ºncias
%X The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals.
%K Piperaceae
%K Piper solmsianum
%K essential oil
%K sarisan
%K psychopharmacologic effect
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004