%0 Journal Article
%T Cell proliferation and viability of HELA and HEP-2P neoplastic cultures in vitro treated with new polyphenolic or polysaccharidic biopreparations of vegetable and fungal origin
%A Pincu Rotinberg
%A Cosmin Mihai
%A Daniela Gherghel
%A Elena Truta
%J Analele £¿tiin£¿ifice Ale Universit£¿£¿ii Alexandru Ioan Cuza din Ia£¿i,Sectiunea II A : Genetica si Biologie Moleculara
%D 2008
%I Alexandru Ioan Cuza University of Iasi
%X The in vitro action of some new autochthonous polysaccharidic and polyphenolic biopreparations, specifically extracted from fungal and vegetable sources, upon the proliferation and viability of the HeLa and Hep-2p cancerous cells was investigated. The significant perturbation of the mitosis process of the tumoral cells, as well as the profound diminution of the cell viability of the neoplastic cell cultures argue the behaviour of some polysaccharidic and polyphenolic extracts as in vitro active cytostatic and cytotoxic agents. This primary characterization of some natural fungal or vegetable extracts as cytostatic and/or cytotoxic agents offers the informational background for the introduction of those biopreparations in the in vivo antitumoral screening program on different experimental tumoral systems.
%U http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/720