%0 Journal Article %T Progressive tumefactive fibroinflammatory lesion of the infratemporal fossa treated by radiation therapy %A Frank J.P. Hoebers %A Bayardo Perez Ordonez %A Jon Irish %A Rand E. Simpson %J Rare Tumors %D 2012 %I PAGEPress Publications %R 10.4081/rt.2012.e12 %X Tumefactive fibroinflammatory lesion (TFIL) is a rare benign tumor in the head and neck region. We present a case of a 40-year-old female with a benign but progressive lesion of the infratemporal fossa, which was diagnosed as TFIL. Patient responded briefly to a course of steroid treatment but eventually showed progression and was unresponsive to further steroids. She was then treated with external beam radiation to a dose of 60 Gy in 30 fractions. After radiation a slow, gradual decrease in tumor size was noted over the course of years and she is free of disease after more than 11 years of follow-up. The major longterm side effect this patient developed was an expected unilateral radiation-induced retinopathy, due to the close proximity of the lesion to the orbit. The dilemma of treatment of benign disease with radiation with potential long-term complications is discussed and a review of the literature on TFIL is presented. %K tumefactive %K fibroinflammatory %K inflammatory %K radiation therapy %U http://www.pagepress.org/journals/index.php/rt/article/view/3342