%0 Journal Article
%T Prevalence of diverticulosis in recurrent Clostridium difficile infection
%A Michael J Lipp
%A Odelya E Pagovich
%A David Rabin
%A Albert D Min
%A Brett B Bernstein
%J World Journal of Gastroenterology
%D 2010
%I Baishideng Publishing Group Co. Limited
%X AIM: To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and relapse.METHODS: Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexible sigmoidoscopy. An age and gender matched control group was used to compare the prevalence of diverticulosis.RESULTS: Twenty-two patients met the study criteria, and the prevalence of diverticulosis in patients with CDAD relapse was 23% compared to 32% in age and sex matched controls (P = 0.44). A significant proportion of patients with CDAD relapse had co-morbidities associated with immune suppression.CONCLUSION: Diverticulosis does not appear to be associated with CDAD relapse.
%K Clostridium difficile
%K Diverticulosis
%K Relapse
%K Immune suppression
%K Clostridium difficile associated disease
%U http://www.wjgnet.com/1007-9327/full/v16/i3/345.htm