%0 Journal Article
%T Decreased aortic root elasticity-as a novel systemic manifestation of the pseudoexfoliation syndrome: an observational study
%A Mete Alpaslan
%A Aylin Karalezli
%A Mehmet Borazan
%A Beng¨¹ Ekinci K£¿ktekir
%J Anadolu Kardiyoloji Dergisi
%D 2012
%I Aves Yayincilik
%X Objective: To assess the aortic root function in patients with pseudoexfoliation syndrome (PEXS). Methods: In this case- controlled observational study, aortic root function in 31 PEXS patients (mean age 71¡À9 years) and 29 controls of similar ages (mean age 69¡À9 years) were evaluated by M-mode transthoracic echocardiography. Aortic cross-sectional compliance (CSC), Peterson¡¯s elastic modulus (index beta), aortic stiffness index (ASI) and aortic root distensibility (ARD) were calculated by M-mode echocardiography to evaluate the aortic root function. The findings of two groups of patients were compared by Mann-Whitney U test.Results: The CSC and ARD were significantly decreased in patients with PEXS. The CSC was 12.2¡À6.3 cm2/mmHg in patients with PEXS and 17.5¡À11.6 cm2/mmHg in the control group (p=0.015). The ARD was 1.56¡À0.80 cm2/dyne in patients with PEXS and 2.23¡À1.48 cm2/dyne in the control group (p=0.021). The other two indices of aortic root function were not significantly different between the two groups.Conclusion: Aortic root function decreases in patients with PEXS. PEXS may be regarded as a risk factor for cardiovascular and cerebrovascular events.
%K Echocardiography
%K aortic root function
%K aorta
%K pseudoexfoliation syndrome
%U http://anakarder.yaysis.com/sayilar/86/buyuk/483-487.pdf