%0 Journal Article
%T Technological advances in radiotherapy for esophageal cancer
%A Milan Vosmik
%A Jiri Petera
%A Igor Sirak
%A Miroslav Hodek
%A Petr Paluska
%A Jiri Dolezal
%A Marcela Kopacova
%J World Journal of Gastroenterology
%D 2010
%I Baishideng Publishing Group Co. Limited
%X Radiotherapy with concurrent chemotherapy and surgery represent the main treatment modalities in esophageal cancer. The goal of modern radiotherapy approaches, based on recent technological advances, is to minimize post-treatment complications by improving the gross tumor volume definition (positron emission tomography-based planning), reducing interfraction motion (image-guided radiotherapy) and intrafraction motion (respiratory-gated radiotherapy), and by better dose delivery to the precisely defined planning target volume (intensity-modulated radiotherapy and proton therapy). Reduction of radiotherapy-related toxicity is fundamental to the improvement of clinical results in esophageal cancer, although the dose escalation concept is controversial.
%K Esophageal cancer
%K Intensity-modulated radiotherapy
%K Positron emission tomography
%K Image-guided radiotherapy
%K Proton therapy
%U http://www.wjgnet.com/1007-9327/full/v16/i44/5555.htm