%0 Journal Article %T Hemoglobin A1c improvements and better diabetes-specific quality of life among participants completing diabetes self-management programs: A nested cohort study %A Abhinav Khanna %A Amber L Bush %A J Michael Swint %A Melissa F Peskin %A Richard L Street %A Aanand D Naik %J Health and Quality of Life Outcomes %D 2012 %I BioMed Central %R 10.1186/1477-7525-10-48 %X We conducted a retrospective cohort study nested within a randomized comparative effectiveness trial of diabetes self-management interventions in 75 diabetic patients. Multiple linear regression models were developed to examine the relationship between change in HbA1c from baseline to one-year follow-up and Diabetes-39 (a diabetes-specific quality of life measure) at one year.HbA1c levels improved for the overall cohort from baseline to one-year follow-up (t (74)£¿=£¿3.09, p£¿=£¿.0029). One-year follow up HbA1c was correlated with worse overall quality of life (r£¿=£¿0.33, p£¿=£¿0.004). Improvements in HbA1c from baseline to one-year follow-up were associated with greater D-39 diabetes control (¦Â = 0.23, p£¿=£¿.04) and D-39 sexual functioning (¦Â = 0.25, p£¿=£¿.03) quality of life subscales.Improvements in HbA1c among participants completing a diabetes self-management program were associated with better diabetes-specific quality of life. Innovations in primary care that engage patients in self-management and improve clinical biomarkers, such as HbA1c, may also be associated with better quality of life, a key outcome from the patient perspective. %K Diabetes-specific quality of life %K Diabetes %K Quality of life %K Diabetes-39 %K Self-management %K Hemoglobin A1c %U http://www.hqlo.com/content/10/1/48/abstract