%0 Journal Article %T Fuzzy Inference Mechanism Based Automatic Elastic Registration of Two-dimensional Gel Electrophoresis Images %A Yonghui Pan %A Zhaohong Deng %A Shitong Wang %A Qun Gao %J Information Technology Journal %D 2012 %I Asian Network for Scientific Information %X A key technique for protein analysis is the geometric alignment of two-dimensional polyacrylamide gel electrophoresis (2-D PAGE), i.e., 2-D PAGE image registration. In this study, the adaptability in elastic image registration was emphasized. According to the characteristics of 2-D gel image registration, a fuzzy-inference-rule based flexible model (FIM-FM) is proposed to model the complex transformation between 2-D gel image pairs. By introducing the concept of motion estimation, the parameter learning rules of the proposed model are derived for registration. The experiments show that the proposed algorithm is highly effective for registration of 2-D gel images and is competitive to the existing state-of-the-art algorithms. %K image matching %K image registration %K adaptive learning %K Fuzzy inference mechanism %K automatic elastic registration %K two-dimensional gel electrophoresis images %U http://docsdrive.com/pdfs/ansinet/itj/2012/20-29.pdf