%0 Journal Article %T Generic and oral quality of life is affected by oral mucosal diseases %A Li-Jun Liu %A Wen Xiao %A Qing-Bo He %A Wei-Wen Jiang %J BMC Oral Health %D 2012 %I BioMed Central %R 10.1186/1472-6831-12-2 %X Five hundred and thirty-eight OMDs were recruited in this study. The instruments applied were Chinese version of the 36-item short form health survey (SF-36) and the short-form of Oral Health Impact Profile (OHIP-14).The mean score of sum OHIP-14 was significantly higher in the patients with OMD (10.81 ¡À 9.01) compared with those in the healthy subjects (HS) (6.55 ¡À 6.73) (p < 0.001, Mann-Whitney U test). 56.51% of the OMD patients and 12.94% of the HS reported at least one oral negative impact (p < 0.001, Chi-square test). The overall mean score of SF-36 was significantly lower in the patients with OMD (74.54 ¡À 12.77) compared with those in the HS (77.97 ¡À 12.39) (p = 0.021, t-test).Administration of specific and generic questionnaires of QoL can provide us a detailed picture of the impact of OMDs on patients, and both generic and oral QoL were impaired in the patients with OMD.Oral mucosal diseases (OMDs) are common, and many of them are unknown cause. For example, recurrent aphthous stomatitis (RAS) affects about 0.5-60% of the population [1,2]. There is no medication gives completely reliable relief. Patients with OMD such as pemphigus, which is a rare but serious and highly disabling immunobullous disease of the skin and mucous membranes, can be suffered from life-threatening symptom and be influenced daily life in many ways. Hence, the consequences of OMDs are not only physical, they are also social and psychological. These diseases seriously impair quality of life (QoL) in a large number of individuals and can affect various aspects of life, including oral function, appearance, and interpersonal relationships [3-5]. Information regarding the impact of OMD on QoL is a recognized need. The importance of embracing patients' views in assessing oral health needs and in treatment planning has been advocated. Therefore a number of different patient centered oral health status measures have been developed over the past decade to assess the physical, social and psycho %U http://www.biomedcentral.com/1472-6831/12/2