%0 Journal Article
%T Sinapyl Alcohol Derivatives from the Lipo-soluble Part of Dichrocephala benthamii C. B. Clarke
%A Xinhui Tian
%A Gang Ding
%A Chaozhong Peng
%A Yanbao Hu
%A Li Li
%A Hong Chen
%A Zhongmei Zou
%J Molecules
%D 2013
%I MDPI AG
%R 10.3390/molecules18021720
%X Four new sinapyl alcohol derivatives dichrocephols A¨CD (compounds 1¨C 4) were isolated from the lipo-soluble part of the whole herb of Dichrocephala benthamii C. B. Clarke, together with the known compound syringenin isovalerate ( 5). Their structures were elucidated on the basis of spectroscopic analysis. Their absolute configurations were established by the method of alkaline hydrohysis. Compounds 1¨C 3 showed moderate cytotoxity against HeLa cells, with IC 50 values of 14.8 ¦ÌM, 51.6 ¦ÌM and 81.6 ¦ÌM, respectively. This is the first time that sinapyl alcohol derivatives were isolated from the genus Dichrocephala.
%K Dichrocephala benthamii C. B. Clarke
%K Asteraceae
%K sinapyl alcohol derivatives
%K absolute configuration determination
%K cytotoxicity
%U http://www.mdpi.com/1420-3049/18/2/1720