%0 Journal Article
%T Two New Koumine-Type Indole Alkaloids from Gelsemium elegans Benth.
%A Mingxue Sun
%A Xiaoli Hou
%A Huanhuan Gao
%A Junsheng Guo
%A Kai Xiao
%J Molecules
%D 2013
%I MDPI AG
%R 10.3390/molecules18021819
%X Two new indole alkaloids, 21-oxokoumine ( 1) and furanokoumine ( 2), were isolated from the roots of Gelsemium elegans Benth together with three known compounds. The structures of the two novel compounds were elucidated by spectroscopic methods, including NMR, HR-ESI-MS, UV, IR, CD and molecular modeling. Compound 1 is the first instance of a koumine-type alkaloid with a carbonyl at the C-21 position, while compound 2 possesses a tetrahydrofuran ring located on C-20 and C-21.
%K indole alkaloids
%K Gelsemium elegans Benth.
%K 21-oxokoumine
%K furanokoumine
%U http://www.mdpi.com/1420-3049/18/2/1819